More than 48 hours after 84-year-old Nancy Guthrie vanished from her home in Tucson, Arizona, investigators say the case is growing more urgent. With the FBI now involved, officials stress that time is critical, especially because Nancy relies on daily medication.

A new, unsettling twist emerged when TMZ reported receiving an email that appears to be a ransom note connected to the disappearance. TMZ says the message demands a very specific amount of money, claims to include insider details about Nancy and her home, and was immediately forwarded to law enforcement.

Authorities have acknowledged they’re aware of possible ransom-related communications but have not confirmed whether any message is real or a hoax. Meanwhile, investigators continue reviewing surveillance footage and pursuing multiple leads as part of the search.

Family statements have focused on one goal: bringing Nancy home safely. Savannah Guthrie has thanked the public for support, while officials urge anyone with even small information to come forward as the investigation continues.