One simple pattern is to multiply the first number by one more than the second number. This gives 1 × (4 + 1) = 5, 2 × (5 + 1) = 12, and 3 × (6 + 1) = 21. Applying the same rule to the final equation gives 5 × (8 + 1) = 45.
However, there is another possible pattern. If each new equation includes the previous answer, then 2 + 5 + 5 = 12 and 3 + 6 + 12 = 21. Following that rule, the final calculation becomes 5 + 8 + 21 = 34. This demonstrates why viral math puzzles like this can sometimes produce more than one reasonable answer.
The article considers 45 the likely intended answer because the same compact rule works independently on every line. Still, the puzzle does not provide enough information to prove that 45 is the only possible solution. The real challenge is therefore not difficult arithmetic, but recognizing hidden patterns and questioning the assumptions behind an apparently simple equation.