Other causes can include acid reflux, certain medications, throat infections, and sleep disorders. Reflux may increase saliva production because the body is trying to protect the throat and esophagus from stomach acid. Some medications can also increase saliva, while infections or problems with swallowing can make it harder to keep saliva in the mouth during sleep.
One condition worth paying attention to is sleep apnea. People with sleep apnea may breathe through their mouths, snore loudly, gasp during sleep, experience pauses in breathing, wake with headaches, or feel unusually tired during the day. In this situation, the drooling itself is usually not the main concern—the possible breathing problem behind it is what may need medical evaluation.
For most people, an occasional damp pillow is nothing to worry about. Changing sleep position, treating nasal congestion, or addressing reflux may help. But if drooling suddenly becomes frequent or excessive, especially when it comes with breathing problems, swallowing difficulties, unusual weakness, or other new symptoms, it is worth speaking with a healthcare professional. Pay attention to changes your body keeps repeating—sometimes a small nighttime habit can be an important clue.